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KMID : 0363620160370030027
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Journal of Korean Oriental Medicine
2016 Volume.37 No. 3 p.27 ~ p.38
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Skin Color Measurement of LU10; Comparison between Functional Dyspepsia Patients and Healthy Controls
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Kim Min-Ji
Ko Seok-Jae
Park Jae-Woo
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Abstract
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Objectives: According to Korean Medicine theory, the skin color of LU10 serves as a diagnostic clue to dyspeptic symptoms. The aims of this study were (1) to find the difference of skin color in LU10 region between functional dyspepsia (FD) and healthy control (HC) and (2) to examine the relationship between LU10 skin color parameters and dyspeptic symptoms.
Methods: 39 participants (29 FD and 10 HC) have participated in this study. They were asked to complete gastrointestinal scale (GIS), gastrointestinal symptom rating scale (GSRS), Nepean dyspepsia index (NDI), functional dyspepsia-related quality of life (FD-QoL), visual analogue scale (VAS) for dyspeptic symptoms, food retention questionnaire (FRQ) and cold heat questionnaire (CHQ). L* (luminance), a* (red-green balance) and b* (yellow-blue balance) values of LU10 region were calculated through digital images of the participant’s hand. Then we evaluated test-retest reliability of L*, a* and b* values of LU10 region. Additionally, we compared L*, a* and b* values of LU10 between FD and HC, and examined the relationship between LU10 color parameters and seven questionnaires scores.
Results: Only L* values in LU10 region were significantly higher in FD compared with HC. GIS scores and the subset scores of NDI had a positive correlation with L* values significantly. Correlation coefficients of test-retest reliability of skin color measurement of LU10 ranged from 0.871 to 0.936 representing very strongly statistically significant (P<0.001).
Conclusions: We confirmed the difference of skin color in LU10 region between FD and HC, and relationship between LU10 skin color parameters and dyspeptic symptoms.
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KEYWORD
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Functional dyspepsia, L*, a, b*, LU10, Korean medicine, Diagnosis
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